I am running Fedora 30 with Xfce 4.13pre3. With the upgrade to xfce4-settings 4.13.8, the following issue happens with display settings when the system has two monitors.
Under display settings -
If I have "Automatically enable profiles when new display is connected" enabled, my saved profiles are ignored. In other words, my setup is completely ignored. However, if I toggle the "Automatically enable profiles ..." setting OFF, my setup works as expected even surviving restart. This was NOT the case with older versions.
$ xfce4-display-settings -v
xfce4-display-settings 4.13.8 (Xfce 4.14pre2)
i am experiencing the same issue that it does not detect the profiles and Display Settings applet would often crash when trying to apply the layout each reboot or when the laptop is docked/undocked everything resets
Simon Steinbeiss referenced this bugreport in commit d403bc6abc9bd49b9f95d1ba647fe112519597dd
display: Remove debug statement breaking profiles (Bug #15769)
Sorry for the inconvenience...